Health and Disease, Uncategorized

Have You Had Mono?

Did you have Mononucleosis?

 

mono

Millions of young Americans have lived through the fatigue and discomfort of mononucleosis.

Now, new research suggests, but doesn’t prove, that the virus that causes the illness may be linked to an increased risk for seven other serious immune-system diseases.

Those diseases include lupus; multiple sclerosis; rheumatoid arthritis; juvenile idiopathic arthritis; inflammatory bowel disease; celiac disease, crohns disease and type 1 diabetes.

“Mono” is a contagious illness that occurs most often in teens and young adults. It’s caused by the Epstein-Barr virus, one of the most common human viruses.

“Epstein-Barr virus infects over 90 percent of adults, and the infection lasts for a lifetime,” said study lead author Dr. John Harley.

“The new results are building a strong case that this virus is also involved in causing a number of autoimmune diseases for at least some patients,” added Harley. He is director of the Cincinnati Children’s Hospital Center for Autoimmune Genomics and Etiology.

“It is the kind of circumstantial evidence that is comparable to a smoking gun,” he added.

And those seven diseases affect roughly 8 million Americans, Harley and his colleagues said.

However, one expert said people who have had mono shouldn’t panic.

The findings “should not be a cause for alarm,” said Dr. David Pisetsky, a professor of medicine at the Duke University School of Medicine in Durham, N.C.

“In modern life everyone has been exposed and infected with Epstein-Barr,” he noted. “And if 99 percent of people have been exposed to Epstein-Barr, and only 0.1 percent have lupus, it means there really must be other factors at play that affect risk,” Pisetsky explained.

“I really don’t think it’s a reason for undue concern,” he added. Pisetsky is also on the scientific advisory board for the Lupus Research Alliance.

Harley’s in-depth genetic analysis revealed that at the cellular level, the Epstein-Barr virus shares a number of abnormal viral on-off switches (“transcription factors”) in common with those seven other illnesses.

Those transcription factors are meant to move along the human genome (DNA roadmap), jumpstarting cells into performing necessary tasks.

But the abnormal switches found in Epstein-Barr hijack this process. First, they bind to a specific protein — known as EBNA2. Then they move about the genome in search of disease trigger points. Once docked at a respective trigger point, the risk for that particular disease goes up, the new research suggests.

Harley said he and other scientists will continue to examine additional factors that likely also contribute to autoimmune risk. Autoimmune diseases occur when your immune system mistakenly attacks your body.

 

 

As the cause of mononucleosis, Epstein-Barr is typically transmitted via saliva, giving rise to its nickname as the “kissing disease.”

Kids and teens with mono may have a fever, muscle aches and sore throat. They often feel exhausted. However, many people — especially young children — experience no symptoms. And in most cases, mono resolves within a couple of weeks.

The new findings stem from an extensive genetic review of potential links between the Epstein-Barr virus and roughly 200 illnesses. However, the study could not prove a cause-and-effect relationship.

The review actually uncovered preliminary links to 94 additional diseases, including breast cancer. But Harley’s team said further investigation is needed to confirm those associations.

Tim Coetzee is chief advocate for services and research with the National Multiple Sclerosis Society. He characterizes the new findings as “an important contribution.”

“We need these kinds of studies to help us unravel how this virus could trigger disease,” he said. “The paper is also a powerful demonstration about how detailed genetic studies can help us understand human diseases.”

Careful research like this, Coetzee added, “will give us the knowledge we need to better understand the complexity of autoimmune diseases, and importantly point the way to potential prevention of these.”

 

Ask yourself if you have had a lot of strep throats, asthma, bronchitis or mono in your life.  Are you one who has allergies, If so, make an appointment with us, and we can work together to prevent any of these diseases from attacking you.

 

Health and Wellness Associates

Archived

P Carrothers

Director of Personalized Health Care

Preventative and Restorative Medicine

312-972-9355 (WELL)

 

HealthWellnessAssociates@gmail.com

 

https://www.facebook.com/HealthAndWellnessAssociates/

Advertisements

1 thought on “Have You Had Mono?”

  1. BEST HEALTH HERBAL CENTRE.

    I was diagnosed with Chronic obstructive pulmonary disease (COPD) and put on Prednisolone on december 29th, 2017. I followed it 100% for a month and could not help me the way am expecting. Finally i began to panic and called my doctor, he told me to get used to it. He said I would be on Prednisolone my whole life. At that point my life messed up and began to do a lot of research. Then I found Seth COPD story (google ” How I reversed my copd with herbal remedies” ) I read that article from end to end because everything Seth was saying made absolute sense. I started using the COPD herbal remedy february this year, product of BEST HEALTH HERBAL CENTRE. There was no diet involved, no side effect which was extremely marvelous. After the first 4 weeks of usage, my shortness of breath, chest tightness and cough disappeared completely. My COPD was totally reversed after 6 weeks of usage. Now am living COPD FREE. Please folks get off drugs and help yourself by trying natural methods.

    Like

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Google+ photo

You are commenting using your Google+ account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

w

Connecting to %s