Rx to Wellness, Uncategorized

Popular Asthma Rx May Not Work

Popular Asthma Rx May Not Work

News Picture: For Many With Mild Asthma, Popular Rx May Not Work: Study

A widely used type of asthma medication may not work in more than half of patients who are prescribed it, new research shows.

Inhaled corticosteroids, which are designed to reduce airway inflammation, are recommended for all patients with persistent asthma.

But this medication’s effectiveness may be limited to a type of inflammation that occurs in far fewer patients than once thought, according to the researchers.

For the study, which was funded by the U.S. National Heart, Lung, and Blood Institute, investigators compared the use of an inhaled steroid called mometasone (Nasonex) to a placebo in 295 patients over 12 years of age with mild persistent asthma.

The patients were grouped according to the level of eosinophils (Eos), a type of white blood cell, in their phlegm. In all, 73% were “Eos low” — about 50% more than the researchers expected. The remaining 27% were “Eos high.”

Among those who were Eos low, there was no significant difference in response to mometasone versus the placebo. And about 66% did as well or better on the placebo, the findings showed.

Eos-high patients were nearly three times more likely to respond to the inhaled steroid than to the placebo (74% versus 26%), according to the study published May 19 in the New England Journal of Medicine.

One lung expert noted inhaled steroids have been used to treat asthma for decades.

“Aerosolized steroids revolutionized the treatment of asthma in the 1990s, and so it is curious to come upon a study wherein more than half of asthmatics studied responded to aerosolized steroid no better than placebo,” said Dr. Len Horovitz, a pulmonary specialist with Lenox Hill Hospital in New York City. But he noted that accurately measuring Eos levels in the phlegm can be difficult.

The researchers also looked at use of a medication called tiotropium (Spiriva), which is prescribed along with inhaled steroids. Tiotropium relaxes the muscles that tighten around the airways in asthma.

Though there was not enough evidence to conclude that patients prescribed tiotropium are likely to do better, the results suggested that alternatives to inhaled steroids should be studied further, the researchers said.

“The take-home message is that many patients have a pattern of inflammation that makes them less likely to respond to inhaled steroids,” explained study first author Dr. Stephen Lazarus. He’s a professor in the division of pulmonary and critical care medicine at the University of California, San Francisco.

“Doctors should consider this if patients are not responding, rather than just increasing the dose,” he suggested in a university news release.

-People Start to Heal The Moment They Are Heard-

 

Health and Wellness Associates
EHS Telehealth

WordPress:  https://healthandwellnessassociates.co/

Advertisements
Lifestyle, Rx to Wellness, Uncategorized

Schizophrenia: Symptoms, Types, Causes, Treatment

Schizophrenia: Symptoms, Types, Causes, Treatment

 

A panoramic concept shows the face of a man with schizophrenia.

 

Schizophrenia is a chronic, severe, debilitating mental illness characterized by disordered thoughts, abnormal behaviors, and anti-social behaviors. It is a psychotic disorder, meaning the person with schizophrenia does not identify with reality at times.

Who is Affected

Schizophrenia affects more than 2 million people in the U.S.

  • Schizophrenia affects about 1.1% of the world’s population
  • 3.5 million Americans have schizophrenia
  • Schizophrenia is most commonly diagnosed between the ages of 16 to 25
  • Schizophrenia can be hereditary (runs in families)
  • It affects men 1.5 times more commonly than women
  • Schizophrenia and its treatment has an enormous effect on the economy, costing between $32.5-$65 billion each year

How Common Is Schizophrenia in Children?

 

Children may also be affected by schizophrenia.

Schizophrenia in young children is rare. The National Institute of Mental Health (NIMH) estimates only 1 in 40,000 children experience the onset of schizophrenia symptoms before the age of 13.

Types of Schizophrenia

Schizophrenia health care check list.

There are five types of schizophrenia (discussed in the following slides). They are categorized by the types of symptoms the person exhibits when they are assessed:

  • Paranoid schizophrenia
  • Disorganized schizophrenia
  • Catatonic schizophrenia
  • Undifferentiated schizophrenia
  • Residual schizophrenia

Paranoid Schizophrenia

A woman suffering from paranoid schizophrenia is distressed.

Paranoid-type schizophrenia is distinguished by paranoid behavior, including delusions and auditory hallucinations. Paranoid behavior is exhibited by feelings of persecution, of being watched, or sometimes this behavior is associated with a famous or noteworthy person a celebrity or politician, or an entity such as a corporation. People with paranoid-type schizophrenia may display anger, anxiety, and hostility. The person usually has relatively normal intellectual functioning and expression of affect.

Disorganized Schizophrenia

A young woman pours a pot of spaghetti on her head.

A person with disorganized-type schizophrenia will exhibit behaviors that are disorganized or speech that may be bizarre or difficult to understand. They may display inappropriate emotions or reactions that do not relate to the situation at-hand. Daily activities such as hygiene, eating, and working may be disrupted or neglected by their disorganized thought patterns.

Catatonic Schizophrenia

A man is in a catatonic state.

Disturbances of movement mark catatonic-type schizophrenia. People with this type of schizophrenia may vary between extremes: they may remain immobile or may move all over the place. They may say nothing for hours, or they may repeat everything you say or do. These behaviors put these people with catatonic-type schizophrenia at high risk because they are often unable to take care of themselves or complete daily activities.

Undifferentiated Schizophrenia

A young man with undifferentiated schizophrenia wears a tinfoil hat while staring into a TV.

Undifferentiated-type schizophrenia is a classification used when a person exhibits behaviors which fit into two or more of the other types of schizophrenia, including symptoms such as delusions, hallucinations, disorganized speech or behavior, catatonic behavior.

Residual Schizophrenia

A schizophrenic girl's reflection shows her inner turmoil.

When a person has a past history of at least one episode of schizophrenia, but the currently has no symptoms (delusions, hallucinations, disorganized speech or behavior) they are considered to have residual-type schizophrenia. The person may be in complete remission, or may at some point resume symptoms.

What Are Causes of Schizophrenia?

Rate of gray matter loss: Composite MRI scan data showing areas of gray matter loss over 5 years, comparing 12 normal teens (left) and 12 teens with childhood-onset schizophrenia. Red and yellow denotes areas of greater loss. Front of brain is at left.

Schizophrenia has multiple, intermingled causes which may differ from person to person, including:

  • Genetics (runs in families)
  • Environment
  • Brain chemistry
  • History of abuse or neglect

Is Schizophrenia Hereditary?

Twin sisters look at each other.

Schizophrenia has a genetic component. While schizophrenia occurs in only 1% of the general population, it occurs in 10% of people with a first-degree relative (parent, sibling) with the disorder. The risk is highest if an identical twin has schizophrenia. It is also more common in people with a second-degree relative (aunts, uncles, cousins, grandparents) with the disorder.

Schizophrenia Symptoms

Intense anxiety is a symptom of schizophrenia.

Many people with schizophrenia do not appear ill. However, many behavioral changes will cause the person to seem ‘off’ as the disease progresses. Symptoms include:

  • Social withdrawal
  • Anxiety
  • Delusions
  • Hallucinations
  • Paranoid feelings or feelings of persecution
  • Loss of appetite or neglecting to eat
  • Loss of hygiene

Symptoms may also be grouped into categories, discussed in the following slides.

Positive (More Overtly Psychotic) Symptoms

A person with schizophrenia may experience psychotic symptoms.

The “positive,” or overtly psychotic, symptoms are symptoms not seen in healthy people, include:

  • Delusions
  • Hallucinations
  • Disorganized speech or behavior
  • Dysfunctional thinking
  • Catatonia or other movement disorders

Negative (Deficit) Symptoms

A man sits by himself.

“Negative” symptoms disrupt normal emotions and behaviors and include:

  • Social withdrawal
  • “Flat affect,” dull or monotonous speech, and lack of facial expression
  • Difficulty expressing emotions
  • Lack of self-care
  • Inability to feel pleasure (anhedonia)

Cognitive Symptoms

A schizophrenic may have difficulty remembering simple tasks.

Cognitive symptoms may be most difficult to detect and these include:

  • Inability to process information and make decisions
  • Difficulty focusing or paying attention
  • Problems with memory or learning new tasks

Affective (or Mood) Symptoms

A depressed woman.

Affective symptoms refer to those which affect mood. Patients with schizophrenia often have overlapping depression and may have suicidal thoughts or behaviors.

How Is Schizophrenia Diagnosed?

Doctor with stethoscope.

The diagnosis of schizophrenia is made both by ruling out other medical disorders that can cause the behavioral symptoms (exclusion), and by observation of the presence of characteristic symptoms of the disorder. The doctor will look for the presence of delusions, hallucinations, disorganized speech or behavior, and/or negative symptoms, along with social withdrawal and/or dysfunction at work or in daily activities for at least six months.

The doctor may use physical examination, psychological evaluation, laboratory testing of blood, and imaging scans to produce a complete picture of the patient’s condition.

How Is Schizophrenia Diagnosed?

A mental-health professional diagnoses a patient.

Mental health screening and evaluation is an important part of the diagnosis process for schizophrenia. Many other mental illnesses such as bipolar disorder, schizoaffective disorder, anxiety disorders, severe depression, and substance abuse may mimic symptoms of schizophrenia. A doctor will perform an assessment to rule out these other conditions.

Schizophrenia Treatment – Medications

Zyprexa 10 mg vial, Abilify Discmelt 15 mg tablet, Risperdal M-Tab 1 mg ODT, Geodon 20 mg vial

Antipsychotic medications are the first-line treatment for many patients with schizophrenia. Medications are often used in combination with other types of drugs to decrease or control the symptoms associated with schizophrenia. Some antipsychotic medications include:

  • olanzapine (Zyprexa)
  • risperidone (Risperdal)
  • quetiapine (Seroquel)
  • ziprasidone (Geodon)
  • aripiprazole (Abilify)
  • paliperidone (Invega)

Schizophrenia Treatment – Medications (Continued)

Lamictal XR 25 mg tablet, Depakote 125 mg sprinkle cap, Zoloft 100 mg tablet, Cymbalta 20 mg capsule

Mood swings and depression are common in patients with schizophrenia. In addition to antipsychotics, other types of medications are used.

Mood stabilizers include:

  • lithium (Lithobid)
  • divalproex (Depakote)
  • carbamazepine (Tegretol)
  • lamotrigine (Lamictal)

Antidepressants include:

  • fluoxetine (Prozac)
  • sertraline (Zoloft)
  • paroxetine (Paxil)
  • citalopram (Celexa)
  • escitalopram (Lexapro)
  • venlafaxine (Effexor)
  • desvenlafaxine (Pristiq)
  • duloxetine (Cymbalta)
  • bupropion (Wellbutrin)

Schizophrenia Treatment – Psychosocial Interventions

Family psycho-education teaches family members problem-solving skills.

Family psycho-education: It is important to include psychosocial interventions in the treatment of schizophrenia. Including family members to support patients decreases the relapse rate of psychotic episodes and improves the person’s outcomes. Family relationships are improved when everyone knows how to support their loved one dealing with schizophrenia.

Schizophrenia Treatment – Psychosocial Interventions (Continued)

A psychiatrist, nurse, case manager, employment counselor, and substance-abuse counselor often make up an ACT team.

Assertive community treatment (ACT): Another form of psychosocial intervention includes use of out-patient support groups. Support teams including psychiatrists, nurses, case managers, and other counselors, meet regularly with the schizophrenic patient to help reduce the need for hospitalization or a decline in their mental status.

Schizophrenia Treatment – Psychosocial Interventions (Continued)

About 50% of individuals with schizophrenia suffer from some kind of substance abuse or dependence.

Substance abuse treatment: Many people with schizophrenia (up to 50%) also have substance abuse issues. These substance abuse issues worsen the behavioral symptoms of schizophrenia and need to be addressed for better outcomes.

Schizophrenia Treatment – Psychosocial Interventions (Continued)

A group socializes around a laptop computer.

Social skills training: Patients with schizophrenia may need to re-learn how to appropriately interact in social situations. This kind of psychosocial intervention involves rehearsing or role-playing real-life situations so the person is prepared when they occur. This type of training can reduce drug use, and improve relationships.

Schizophrenia Treatment – Psychosocial Interventions (Continued)

A woman helps a job applicant fill out forms.

Supported employment: Many people with schizophrenia have difficulty entering or re-entering the work force due to their condition. This type of psychosocial intervention helps people with schizophrenia to construct resumes, interview for jobs, and even connects them with employers willing to hire people with mental illness.

Schizophrenia Treatment – Psychosocial Interventions (Continued)

A doctor uses cognitive behavioral therapy (CBT) intervention with a patient.

Cognitive behavioral therapy (CBT): This type of intervention can help patients with schizophrenia change disruptive or destructive thought patterns, and enable them to function more optimally. It can help patients “test” the reality of their thoughts to identify hallucinations or “voices” and ignore them. This type of therapy may not work in actively psychotic patients, but it can help others who may have residual symptoms that medication does not alleviate.

Schizophrenia Treatment – Psychosocial Interventions (Continued)

Weight gain can be a side effect of some antipsychotic and other psychiatric medications.

Weight management: Many anti-psychotic and psychiatric drugs cause weight gain as a side effect. Maintaining a healthy weight, eating a well-balanced diet, and exercising regularly helps prevent or alleviate other medical issues.

What Is the Prognosis for Schizophrenia?

A family supports each other.

The prognosis for people with schizophrenia can vary depending on the amount of support and treatment the patients receives. Many people with schizophrenia are able to function well and lead normal lives. However, people with schizophrenia have a higher death rate and higher incidence of substance abuse. When medications are taken regularly and the family is supportive, patients can have better outcomes.

 

-People Start to Heal The Moment They Are Heard- 

Health and Wellness Associates
healthwellnessassociates@gmail.com
Health and Disease, Rx to Wellness, Uncategorized

Loose Your Empathy when on Pain Relievers

Pain Relievers Reduce Empathy

Because of the opioid epidemic doctors are prescribing other pain relievers including gabapentin, pregabalin (Lyrica) and tramadol. How safe are they?

The ability to put yourself in someone else’s shoes is at the heart of the Sandra Bullock/Quinton Aaron “The Blind Side,” which is based on the true story of a remarkable young man named Michael Oher.

At 16, Michael was taken in by an empathetic family, and with their support he went from being homeless to having a successful NFL career, even winning a Super Bowl ring while playing right tackle for the Baltimore Ravens.

Empathy is powerful stuff. When you can understand another person’s thoughts and feelings, from his or her point of view, you build common ground, friendship, love, and community.

But research shows that there’s been a 40% decline in empathy in America over the past 20 years. While you may point to this or that external event as the cause, it turns out there’s another source: pain relief medications.

Researchers from Ohio University have found in multiple, double-blind studies that taking acetaminophen reduces your ability to empathize with another person’s pain and pleasure.

And because 23% of U.S. adults take acetaminophen every week (it’s in 600 different medications), that adds up to a lot of less-than-generous feelings floating around.

Here’s a side effect of America’s chronic pain epidemic — around 50 million Americans are afflicted — that very few people have reckoned with.

We suggest opting for lifestyle adjustments — such as improved nutrition, better sleep, weight management, and more physical activity — to control pain.

That way, you can take fewer pain-relieving meds, and increase your public commitment to empathy.

 

-People Start to Heal The Moment They Are Heard-

Health and Wellness Associates
EHS Telehealth

Dr. M Williams

 

 

Rx to Wellness, Uncategorized

The Healing Benefits of Spirulina

The Healing Benefits of Spirulina

Spirulina is a blue-green algae, which is a freshwater plant. It is one of the most researched plants in the recent times. Renowned for its intense flavor, spirulina is gaining popularity for its powerful nutrition profile and benefits.

Spirulina is often deemed the most nutritionally complete of all foods and has countless uses as a supplement for maintaining good health and preventing diseases. This is because it contains a plentiful supply of many important nutrients and antioxidants, including protein, complex carbohydrates, iron, and vitamins A and K, as well as B complex. It’s also rich in chlorophyll, fatty and nucleic acids, and lipids. Spirulina is rich in gamma-linolenic acid, or GLA, a compound found in breast milk that helps develop healthier babies.

Best Source of Beta-Carotene

Spirulina provides a profusion of carotenoids such as best-carotene and yellow xanthophylls. In fact, spirulina is the richest beta-carotene food. The beta-carotene found in spirulina is ten times more concentrated than carrots.

Iron-Rich

Iron is essential for building a strong internal system, yet it is one of the most common mineral deficiencies (zinc is the most common). Spirulina is rich in iron, magnesium and trace minerals and is easier to absorb than iron supplements. Ten grams of spirulina can supply up to 70% of the minimum daily requirements for iron.

Protein Packed

About 60% of spirulina’s dry weight is protein, which in the form it comes in within spirulina, is essential for growth and cell regeneration. It’s a good replacement for fatty meat and dairy products.

 

Builder of Beneficial Flora

Spirulina suppresses bad bacteria like E. coli and stimulates beneficial flora like lactobacillus and bifidobactria in the digestive tract to promote healthy digestion and proper bowel function.

Healthy flora is one of the foundations of good health. It increases the body’s ability to absorb nutrients from the foods we eat and helps protect against infection.

Detoxifier

Spirulina has a completely unique composition of phytonutrients, including chlorophyll, phycocyanin and polysaccharides, that can help to purge toxins from the body. In 1994, a Russian Patent was awarded for spirulina, deeming it a medical food for reducing allergic reactions from radiation sickness. This was a result of 270 children in Chernobyl consuming five grams a day for 45 days. Radionucleides were lowered by 50% and allergic sensitivities were normalized.

Critical For Removing Toxic Heavy Metals

Spirulina is essential for removing heavy metals such as mercury, aluminum, lead, cadmium, and toxic copper from the liver, reproductive system, intestinal tract, thyroid, and brain. Getting rid of these metals gets rid of some of the most favored food of viruses, which are behind many chronic illnesses and symptoms, including autoimmune diseases.

When consumed within 24 hours of each other, barley grass juice powder, spirulina, cilantro, wild blueberries, and Atlantic dulse provide the most effective method on the planet of removing heavy metals. These foods each have their singular strengths, performing slightly different roles in the detoxification process.

During the removal process, metals can get “dropped” or dispersed back into the organs, at which point another member of the team will swoop in, grab the metal, and continue the journey toward the finish line. I call this “pass the football.” On its own, each individual player isn’t 100 percent effective; as a team, they are your anti–heavy metal secret weapon!

Important For Any Chronic Illness & Symptom

Spirulina is an important supplement for anyone with any chronic illness or symptom, or for anyone who wishes to help prevent illness or symptoms in the future.

  • Helps restore brain tissue and rebuilds the central nervous system
  • Helps stabilize glucose levels in the blood
  • Provides critical micronutrients for the thyroid and to bolster the endocrine system
  • Removes not only heavy metals but also other toxins from the liver, intestinal tract, brain, nervous system and thyroid
  • Helps grow fresh neurons and strengthen neurotransmitters
  • Contains high levels of superoxide dismutase (SOD) and chromium, which reinforce adrenal strength
  • Helps to remove radioactive iodine from the thyroid over time, bringing what’s left of the gland back to life in a balanced manner
  • Contains iodine that’s very effective at acting as an antiseptic against Epstein-Barr virus (the cause of thyroid problems) cells in the thyroid
  • Can reduce the growth of nodules, tumors, and cysts (both cancerous and benign)
  • Stops viral and bacterial growth inside the liver
  • Strengthens the liver’s immune system, and helps in its over 2,000 chemical functions
  • Aids the liver’s glucose storage and protein conversions

An Athlete’s Best Friend

Spirulina increases stamina levels in athletes and its rich nutrient content and bioavailable protein content helps build muscle mass. It can curb hunger that may develop during demanding training routines, helping to maintain an athlete’s ideal body weight.

Other Potential Benefits

Promotes healthy eyes, great for anti-aging, helps protect against infection, great for digestive health, increases absorption of nutrients from food, eliminates mercury and other deadly toxins commonly inside the body, helps prevent the onset of cardiovascular diseases, and more.

Healing Tip

High-quality spirulina is the best protein powder you can use in morning drinks and smoothies. Try having it in the Medical Medium Heavy Metal Detox Smoothie daily for tremendous benefits. It is the easiest to digest and by far the most beneficial out of all the protein powders. It deeply replenishes the body with much needed mineral and micro-nutrients. It’s a whole food vitamin and mineral and protein powder packed into one.

Tasty Tip

Sprinkle over watermelon or add to Thai coconut water.

I would not advise going to the local drug store to buy this product.  I only trust two companies that are making it and approved

USA Grown Spirulina

 

https://shop.mercola.com/product/845/spiru-blue-120-tablets-30-day-supply

 

Health and Wellness Associates

Archived

312-972-9355

Dr. Mark Williams

Healthwellnessassociates@gmail.com

https://www.facebook.com/HealthAndWellnessAssociates/

 

Rx to Wellness, Uncategorized

SIDS Risk : Smoking!

Smoking While Pregnant Sends SIDS Risk Soaring

News Picture: Smoking While Pregnant Sends SIDS Risk Soaring

Smoking during pregnancy is never a good idea, but new research shows it might double the risk of a baby dying from sudden infant death syndrome(SIDS).

“Any maternal smoking during pregnancy — even just one cigarette a day — doubles the risk of sudden unexpected infant death [SID, another term for unexplained infant deaths],” said lead researcher Tatiana Anderson. She is a fellow at Seattle Children’s Research Institute, Center for Integrative Brain Research.

Doctors should strongly encourage women to give up smoking during pregnancy, or if they can’t quit, to smoke less, she said. Each cigarette smoked increases the risk of SIDS, Anderson added.

If women didn’t smoke during pregnancy, the rate of SIDS in the United States could be cut by 22 percent, preventing some 800 infant deaths a year, according to the new report published online March 11 in the journal Pediatrics.

Although 55 percent of the women in the study who smoked didn’t stop or cut back during pregnancy, those who did markedly reduced the risk of SIDS, Anderson said.

Specifically, women who cut down on their smoking by the third trimester reduced the risk of SIDS by 12 percent. Women who quit by the third trimester reduced the risk by 23 percent, the researchers found.

For the study, Anderson and her colleagues collected data on more than 19,000 SID cases. SID cases include sudden infant death syndrome and other unknown causes of death, as well as suffocation and strangulation in bed of infants under age 1.

It’s not just smoking, said Dr. Rahul Gupta, chief medical and health officer at the March of Dimes. But the more women smoke, the greater the risk for SID becomes, he said.

Women should stop smoking before pregnancy and certainly during pregnancy, Gupta advised.

Smoking during pregnancy can impair the baby’s brain development. In addition, women who smoke are depriving their baby of oxygen, as smoking decreases the amount of oxygen in the blood and, therefore, in the placenta, he explained.

“Smoking also causes preterm birth, decreases in development of the brain and respiratory system of the baby,” Gupta said. “Nicotine has also been linked with an important part of the development of the brainstem in the infant.”

Gupta explained that if an infant stops breathing during sleep, a mechanism in the brain senses the lack of oxygen and triggers breathing to start. This is called auto-resuscitation.

Nicotine, however, alters this response, he said. “That baby may not be able to auto-resuscitate, and as a result, we end up with sudden infant death syndrome,” Gupta said.

Because e-cigarettes are a nicotine delivery device, they are not a safe alternative to cigarettes, he added.

“Nicotine is in the vaping device, so all the impacts we are talking about are still harmful when nicotine is delivered, regardless of the device,” Gupta said. “Nicotine and babies do not match.”

In addition, flavorings and other ingredients in e-cigarettes may be harmful to developing babies, he noted.

“Quitting smoking is one of the most effective actions you can take to protect yourself and your baby,” Gupta said.

 

-People Start to Heal The Moment They Are Heard- 

 

 

Health and Wellness Associates
EHS Telehealth
Dr P Carrothers
Dr  Rahul Gupta

WordPress:  https://healthandwellnessassociates.co/

 

 

Health and Disease, Rx to Wellness, Uncategorized

Diabetes Drugs and Flesh Eating Infection

Newer Diabetes Drugs Linked to ‘Flesh-Eating’ Genital Infection

News Picture: Newer Diabetes Drugs Linked to 'Flesh-Eating' Genital Infection

 

Say you have type 2 diabetes and you are taking a newer class of medications to treat your disease — but one day you notice pain, redness and a foul odor in your genital area.

If this happens, new research suggests you need to see your doctor immediately, because you may be suffering from Fournier gangrene. Also known as a “flesh-eating” disease, this infection attacks your genital or anal region and can quickly kill tissue as it spreads rapidly.

Unfortunately, it has become a rare but still possible safety concern for people taking diabetes medications known as SGLT2 inhibitors, according to U.S. Food and Drug Administration scientists.

SGLT2 inhibitors are a newer class of diabetes medications, introduced in 2013. Drugs in this class include canagliflozin (Invokana), dapagliflozin (Farxiga) and empagliflozin (Jardiance).

Fournier gangrene occurred in 55 people taking these drugs between March 2013 and January 2019. For comparison, the researchers looked for cases of Fournier gangrene in people taking other diabetes medications from 1984 to 2019. They found only 19 such cases.

Still, the risk for Fournier gangrene remains very low, the researchers stressed.

“In 2017, an estimated 1.7 million patients received a dispensed prescription for an SGLT2 inhibitor,” said study author Dr. Susan Bersoff-Matcha, a medical officer in the FDA’s Center for Drug Evaluation and Research. So, “Fournier gangrene is a rare event,” she said. “While our study shows an association between treatment with SGLT2 inhibitors and Fournier gangrene, we don’t know exactly what the risk is, or if Fournier gangrene can be predicted.”

Broad-spectrum antibiotics and surgery to remove the dead tissue are treatment options, the researchers said.

SGLT2 inhibitors work in the kidneys, allowing excess blood sugar to be removed in the urine, they said.

In addition to lowering blood sugar levels, the drugs may also reduce the risk of heart disease and stroke in some people with type 2 diabetes.

But possible side effects include urinary tract infections and genital infections, such as yeast infections. Kidney problems can also be a concern with this class of medications.

All of the patients with Fournier gangrene identified in this study needed to be hospitalized. Some had several surgeries. Three of the 55 people died from Fournier gangrene.

The average age of the people with Fournier gangrene was 56. Thirty-nine were men. Forty-one cases occurred in the United States. Thirty-one of the 55 cases identified were also taking an additional diabetes medication.

Of those with Fournier gangrene, 21 were using canagliflozin, 16 were using dapagliflozin and 18 were taking empagliflozin, the study said.

Dr. Joel Zonszein, director of the clinical diabetes center at Montefiore Medical Center in New York City, said that while the study was well-done, it cannot prove a cause-and-effect link between the drugs and the disease.

“Infections of the pubic and rectal area are quite common in people with diabetes, they don’t have Fournier’s. Fournier’s is a very aggressive, but extremely rare, disease,” said Zonszein, who wasn’t involved with the study.

When Fournier gangrene does occur, it’s hard to know if it is caused by a medication. He pointed out that a number of clinical trials have been done on SGLT2 inhibitors that have included tens of thousands of people, and there haven’t been any reports of Fournier gangrene.

“I counsel my patients about infections in the genitalia. The main concern is to be aware that they can occur. And, providers need to be more aware of Fournier’s. They have to immediately try to establish the cause of infection and aggressively treat it if they suspect Fournier gangrene,” Zonszein said.

He said a far bigger concern is uncontrolled diabetes and the risk of complications when blood sugar levels aren’t controlled. “The benefits of these medications outweigh the risks,” he said.

In a statement, Boehringer Ingelheim, the company that makes Jardiance (empagliflozin), said the company actively monitors for side effects related to their medications.

“We remain confident in the positive benefit-risk profile of empagliflozin, and empagliflozin-containing products, as outlined in the prescribing information,” the statement from Boehringer Ingelheim said.

The prescribing information of all SGLT2’s was recently changed to reflect the possible risk of Fournier gangrene, as directed by the FDA.

Janssen Pharmaceuticals, maker of Invokana (canagliflozin), and AstraZeneca, maker of Farxiga (dapagliflozin), did not respond to requests for comment.

 

 

If they advertise it on Television, Dont take it!

 

-People Start to Heal The Moment They Are Heard-

Health and Wellness Associates
EHS Telehealth
Dr Gemma Carney
Annals of Internal Medician

WordPress:  https://healthandwellnessassociates.co/

Rx to Wellness, Uncategorized

Amlodipine or Norvasc

Amlodipine or Norvasc

 

Amlodipine is used alone or together with other medicines to treat angina (chest pain) and high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Amlodipine is a calcium channel blocker. It affects the movement of calcium into the cells of the heart and blood vessels. As a result, amlodipine relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor’s prescription.

Drug Interactions

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Atazanavir
  • Ceritinib
  • Clarithromycin
  • Clopidogrel
  • Conivaptan
  • Cyclosporine
  • Dantrolene
  • Digoxin
  • Domperidone
  • Droperidol
  • Fosnetupitant
  • Lacosamide
  • Netupitant
  • Piperaquine
  • Rifampin
  • Ritonavir
  • Simvastatin
  • Tacrolimus
  • Tegafur
  • Telaprevir

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Indinavir

 

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Angina (chest pain) or
  • Heart attack, acute or
  • Heart or blood vessel disease (e.g., coronary artery disease) or
  • Hypotension (low blood pressure)—Use with caution. May make these conditions worse.
  • Heart disease or other heart problems (e.g., aortic stenosis)—Use with caution. The blood pressure-lowering effects of this medicine may be increased.
  • Liver disease—Use with caution. The effects may be increased because of slower removal of the medicine from the body.

Proper Use

 

Take this medicine exactly as directed even if you feel well and do not notice any chest pain. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. Do not miss any doses.

For patients taking this medicine for high blood pressure:

  • In addition to the use of the medicine, treatment for your high blood pressure may include weight control and a change in the types of food you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.
  • Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.
  • Remember that this medicine will not cure your high blood pressure but it does help control it. Therefore, you must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life . If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

You may take this medicine with or without food.

Take this medicine at the same time each day.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For oral dosage form (tablets):
    • For angina (chest pain):
      • Adults—5 to 10 milligrams (mg) once a day.
      • Children—Use and dose must be determined by your doctor.
    • For high blood pressure:
      • Adults—At first, 2.5 to 5 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 10 mg once a day.
      • Children 6 to 17 years of age—2.5 to 5 mg once a day.
      • Children younger than 6 years of age—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Do not take this medicine if it has been more than 12 hours since you missed your last dose.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions

It is very important that your doctor check your progress at regular visits to make sure this medicine is working properly. Blood tests may be needed to check for unwanted effects.

Dizziness, lightheadedness, or fainting may also occur if you exercise or if the weather is hot. Heavy sweating can cause loss of too much water and result in low blood pressure. Use extra care during exercise or hot weather.

If you have been using this medicine regularly for several weeks, do not suddenly stop using it. Stopping suddenly may cause your chest pain or high blood pressure to come back or get worse. Check with your doctor for the best way to reduce gradually the amount you are taking before stopping completely.

Chest pain resulting from exercise or physical exertion is usually reduced or prevented by this medicine. This may tempt you to be too active. Make sure you discuss with your doctor a safe amount of exercise for your medical problem.

After taking a dose of this medicine you may get a headache that lasts for a short time. This should become less noticeable after you have taken this medicine for a while. If this effect continues, or if the headaches are severe, check with your doctor.

In some patients, tenderness, swelling, or bleeding of the gums may appear soon after treatment with this medicine is started. Brushing and flossing your teeth carefully and regularly and massaging your gums may help prevent this. See your dentist regularly to have your teeth cleaned. Check with your doctor or dentist if you have any questions about how to take care of your teeth and gums, or if you notice any tenderness, swelling, or bleeding of your gums.

Do not take other medicines unless they have been discussed with your doctor. This especially includes over-the-counter (nonprescription) medicines for appetite control, asthma, colds, cough, hay fever, or sinus problems, since they may increase your blood pressure.

Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

  1. Swelling of the ankles or feet

Less common

  1. Difficult or labored breathing
  2. dizziness
  3. fast, irregular, pounding, or racing heartbeat or pulse
  4. feeling of warmth
  5. redness of the face, neck, arms, and occasionally, upper chest
  6. shortness of breath
  7. tightness in the chest
  8. wheezing

Rare

  1. Black, tarry stools
  2. bleeding gums
  3. blistering, peeling, or loosening of the skin
  4. blood in the urine or stools
  5. blurred vision
  6. burning, crawling, itching, numbness, prickling, “pins and needles”, or tingling feelings
  7. chest pain or discomfort
  8. chills
  9. cold and clammy skin
  10. cold sweats
  11. confusion
  12. dark yellow urine
  13. cough
  14. diarrhea
  15. dilated neck veins
  16. dizziness or lightheadedness when getting up from a lying or sitting position
  17. extra heartbeats
  18. extreme fatigue
  19. fainting
  20. fever
  21. itching of the skin
  22. joint or muscle pain
  23. large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  24. numbness and tingling of the face, fingers, or toes
  25. pain in the arms, legs, or lower back, especially pain in the calves or heels upon exertion
  26. painful or difficult urination
  27. pale, bluish-colored, or cold hands or feet
  28. pinpoint red or purple spots on the skin
  29. red, irritated eyes
  30. redness of the face, neck, arms, and occasionally, upper chest
  31. redness, soreness or itching skin
  32. shakiness in the legs, arms, hands, or feet
  33. slow or irregular heartbeat
  34. sore throat
  35. sores, ulcers, or white spots on the lips or in the mouth
  36. sores, welting, or blisters
  37. sudden sweating
  38. sweating
  39. swelling of the face, fingers, feet, or lower legs
  40. swollen glands
  41. trembling or shaking of the hands or feet
  42. unsteadiness or awkwardness
  43. unusual bleeding or bruising
  44. unusual tiredness or weakness
  45. weak or absent pulses in the legs
  46. weakness in the arms, hands, legs, or feet
  47. weight gain
  48. yellow eyes or skin

Incidence not known

  1. Abdominal or stomach pain
  2. clay-colored stools
  3. diarrhea
  4. headache
  5. loss of appetite
  6. nausea
  7. rash
  8. unpleasant breath odor
  9. vomiting of blood
  10. yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

  1. Acid or sour stomach
  2. belching
  3. heartburn
  4. indigestion
  5. lack or loss of strength
  6. muscle cramps
  7. sleepiness or unusual drowsiness
  8. stomach discomfort, upset, or pain

Rare

  1. Abnormal dreams
  2. anxiety
  3. back pain
  4. bad unusual or unpleasant (after) taste
  5. bleeding gums
  6. blistering, crusting, irritation, itching, or reddening of the skin
  7. bloating
  8. bloody nose
  9. burning feeling in the chest or stomach
  10. burning while urinating
  11. burning, dry, or itching eyes
  12. change in color of the treated skin
  13. change in sense of smell
  14. change in taste
  15. changes in vision
  16. constipation
  17. continuing ringing or buzzing or other unexplained noise in the ears
  18. cracked, dry, or scaly skin
  19. decreased sexual performance or desire
  20. depression
  21. difficulty with moving
  22. difficulty with swallowing
  23. discharge, excessive tearing
  24. double vision
  25. dry mouth
  26. dryness of the skin
  27. excess air or gas in the stomach or intestines
  28. excessive muscle tone
  29. eye pain
  30. feeling of constant movement of self or surroundings
  31. feeling of unreality
  32. feeling unusually cold
  33. flushed, dry skin
  34. fruit-like breath odor
  35. full feeling
  36. general feeling of discomfort or illness
  37. hair loss or thinning of the hair
  38. headache, severe and throbbing
  39. hearing loss
  40. hyperventilation
  41. increased appetite
  42. increased hunger
  43. increased sweating
  44. increased thirst
  45. increased urge to urinate during the night
  46. increased urination
  47. irritability
  48. irritation in the mouth
  49. lack of feeling or emotion
  50. loose stools
  51. loss of memory
  52. muscle pains or stiffness
  53. muscle tension or tightness
  54. muscle weakness
  55. nervousness
  56. pain
  57. pains in the stomach, side, or abdomen, possibly radiating to the back
  58. passing gas
  59. problems with memory
  60. redness and swelling of the gums
  61. redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid
  62. restlessness
  63. runny nose
  64. seeing double
  65. sensation of spinning
  66. sense of detachment from self or body
  67. shakiness and unsteady walk
  68. shivering
  69. sleeplessness
  70. sneezing
  71. stuffy nose
  72. sweating
  73. swollen joints
  74. tenderness in the stomach area
  75. thirst
  76. trouble in holding or releasing urine
  77. trouble sleeping
  78. twitching
  79. unable to sleep
  80. uncaring
  81. unexplained weight loss
  82. unsteadiness, trembling, or other problems with muscle control or coordination
  83. waking to urinate at night
  84. weight loss

Incidence not known

  1. Swelling of the breasts or breast soreness in both females and males

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

-People Start to Heal The Moment They Are Heard-

Health and Wellness Associates
EHS Telehealth

WordPress:  https://healthandwellnessassociates.co/

Rx to Wellness, Uncategorized

Are You Taking Buspirone : Buspar or Vanspar

Buspirone (Oral Route)

 

Mayo Clinic: Opioid Prescribing Has Not Changed — Pain News Network

US Brand Name

  1. Buspar
  2. Buspar Dividose
  3. Vanspar

Descriptions

 

Buspirone is used to treat certain anxiety disorders or to relieve the symptoms of anxiety. However, buspirone usually is not used for anxiety or tension caused by the stress of everyday life.

It is not known exactly how buspirone works to relieve the symptoms of anxiety. Buspirone is thought to work by decreasing the amount and actions of a chemical known as serotonin in certain parts of the brain.

This medicine is available only with your doctor’s prescription.

 

Before Using

The Following Information was prepared by the Mayo Clinic, Rochester MN.

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

IBS, Celiac Disease, Hodgkins Lymphoma, Crohns Disease, Gastric ByPass Patients, and other digested conditions, taking it in tablet form my increase your symptoms.

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies on the relationship of age to the effects of buspirone have not been performed in the pediatric population. However, no pediatric-specific problems have been documented to date.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of buspirone in the elderly.

Pregnancy

Information about this buspirone-oral-route
Pregnancy Category Explanation
All Trimesters B Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate studies in pregnant women OR animal studies have shown an adverse effect, but adequate studies in pregnant women have failed to demonstrate a risk to the fetus.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Drug Interactions

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Do not eat grapefruit or drink grapefruit juice, orange juice, tomato juice, or other heavily citric juices while you are taking this medicine.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

  • Isocarboxazid
  • Linezolid
  • Phenelzine
  • Tranylcypromine

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Alfentanil
  • Almotriptan
  • Amitriptyline
  • Amoxapine
  • Amphetamine
  • Benzhydrocodone
  • Benzphetamine
  • Bromazepam
  • Bromopride
  • Buprenorphine
  • Butorphanol
  • Carbinoxamine
  • Ceritinib
  • Clorgyline
  • Clozapine
  • Cobicistat
  • Codeine
  • Conivaptan
  • Desvenlafaxine
  • Dextroamphetamine
  • Dihydrocodeine
  • Dolasetron
  • Doxylamine
  • Duvelisib
  • Escitalopram
  • Esketamine
  • Fentanyl
  • Flibanserin
  • Fosnetupitant
  • Granisetron
  • Hydrocodone
  • Hydromorphone
  • Hydroxytryptophan
  • Idelalisib
  • Iproniazid
  • Ivosidenib
  • Larotrectinib
  • Levomilnacipran
  • Levorphanol
  • Lisdexamfetamine
  • Lithium
  • Lofexidine
  • Lorcaserin
  • Lorlatinib
  • Loxapine
  • Lumacaftor
  • Meclizine
  • Meperidine
  • Metaxalone
  • Methadone
  • Methamphetamine
  • Methylene Blue
  • Metoclopramide
  • Midazolam
  • Mirtazapine
  • Moclobemide
  • Morphine
  • Morphine Sulfate Liposome
  • Nalbuphine
  • Netupitant
  • Nialamide
  • Oxycodone
  • Oxymorphone
  • Palonosetron
  • Pargyline
  • Pentazocine
  • Periciazine
  • Procarbazine
  • Remifentanil
  • Scopolamine
  • Selegiline
  • Sertraline
  • Sodium Oxybate
  • Sufentanil
  • Tapentadol
  • Toloxatone
  • Tramadol
  • Trazodone
  • Vilazodone
  • Vortioxetine
  • Ziprasidone
  • Zolpidem

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Diltiazem
  • Erythromycin
  • Fluoxetine
  • Ginkgo
  • Haloperidol
  • Itraconazole
  • Nefazodone
  • Rifampin
  • St John’s Wort
  • Verapamil

Other Interactions

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.

  • Grapefruit Juice

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Kidney disease or
  • Liver disease—Effects may be increased because of slower removal of the medicine from the body.

Proper Use

Drug information provided by: IBM Micromedex

Take buspirone only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of unwanted effects.

This medicine comes with a patient information insert. Read and follow the instructions in the insert carefully. Ask your doctor if you have any questions.

You may take this medicine with or without food, but take it the same way each time.

Do not eat grapefruit or drink grapefruit juice, orange juice, tomato juice, or other heavily citric juices while you are taking this medicine.

After you begin taking buspirone, 1 to 2 weeks may pass before you begin to feel the effects of this medicine.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For oral dosage form (tablets):
    • For anxiety:
      • Adults—At first, 7.5 mg two times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 60 mg a day.
      • Children—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.   ( We always recommend calling the local Veterinarian Office to see if he can use it)

 

Precautions

Drug information provided by: IBM Micromedex

If you will be using buspirone regularly for a long time, your doctor should check your progress at regular visits to make sure the medicine is working properly and does not cause unwanted effects.

Do not take buspirone if you are also taking a drug with monoamine oxidase (MAO) inhibitor activity (e.g., isocarboxazid [Marplan®], phenelzine [Nardil®], selegiline [Eldepryl®], or tranylcypromine [Parnate®]). If you do, you may develop extremely high blood pressure.

This medicine will add to the effects of alcohol, ( so no alcohol ) and other CNS depressants (medicines that make you drowsy or less alert). Some examples of CNS depressants are antihistamines or medicine for hay fever, other allergies, or colds; sedatives, tranquilizers, or sleeping medicine; prescription pain medicine or narcotics; barbiturates; medicine for seizures; muscle relaxants; or anesthetics, including some dental anesthetics. Check with your medical doctor or dentist before taking any of the above while you are taking this medicine.

Buspirone may cause some people to become dizzy, lightheaded, drowsy, or less alert than they are normally. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are dizzy or are not alert.

Avoid drinking alcoholic beverages while you are using this medicine.

Do not suddenly stop taking this medicine without checking first with your doctor. Your doctor may want you to gradually reduce the amount you are taking before stopping it completely. This is to decrease the chance of having withdrawal symptoms such as increased anxiety; burning or tingling feelings; confusion; dizziness; headache; irritability; nausea; nervousness; muscle cramps; sweating; trouble with sleeping; or unusual tiredness or weakness.

If you think you or someone else may have taken an overdose of buspirone, get emergency help at once. Symptoms of an overdose are dizziness or light headedness; severe drowsiness or loss of consciousness; stomach upset, including nausea or vomiting; or very small pupils of the eyes.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Side Effects

Drug information provided by: IBM Micromedex

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Rare

  1. Chest pain
  2. confusion
  3. fast or pounding heartbeat
  4. fever
  5. incoordination
  6. mental depression
  7. muscle weakness
  8. numbness, tingling, pain, or weakness in the hands or feet
  9. skin rash or hives
  10. sore throat
  11. stiffness of the arms or legs
  12. uncontrolled movements of the body

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

  1. Dizziness or light headedness especially when getting up from a sitting or lying position suddenly
  2. drowsiness (severe)
  3. loss of consciousness
  4. nausea or vomiting
  5. stomach upset
  6. very small pupils of the eyes

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  1. Restlessness, nervousness, or unusual excitement

Less common or rare

  1. Blurred vision
  2. clamminess or sweating
  3. decreased concentration
  4. diarrhea
  5. drowsiness
  6. dryness of the mouth
  7. muscle pain, spasms, cramps, or stiffness
  8. ringing in the ears
  9. trouble with sleeping, nightmares, or vivid dreams
  10. unusual tiredness or weakness

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

 

 

People Start to Heal, The Moment They Feel They are Heard

Health and Wellness Associates
EHS Telehealth

WordPress:  https://healthandwellnessassociates.co/

Rx to Wellness, Uncategorized

Nexium, Prilosec and Prevacid : The Heartburn Meds That Are Bad For You

Smoking Gun for Stomach Drugs

 

Dangers of Proton Pump Inhibitors

 

Acid-Suppressing Medicine Can Deplete the Body of Needed Magnesium - The People's Pharmacy® #Lansoprazole #Magnesium #PPI #Prilosec #acidsuppressingdrugs #Prevacid #lansoprazoleomeprazole #heartburn #MedicationSideEffects #DrugSideEffectsProton pump inhibitors (PPIs) are among the most widely used medications in the U.S. This class of drug is used to treat chronic heartburn. Although the pain often happens in the lower to mid chest area, it is not related to heart disease or a heart attack.

Instead, heartburn pain happens when acid refluxes up your esophagus, burning the tissue. The fluid in your stomach is highly acidic, necessary for digestion of your food, protection against bacteria and absorption of many nutrients.

A variety of different reasons can cause this acidic fluid to pass the lower esophageal sphincter (LES) and burn your esophagus, but most cases of heartburn are due either to a hiatal hernia or Helicobacter pylori (H. pylori) infection.

Occasional heartburn is best treated with simple lifestyle changes, such as drinking a bit of apple cider vinegar in water right before or after your meals. Unfortunately, when you experience chronic pain over many weeks, your physician may prescribe a daily medication. PPIs are one class of those medications.

The top selling PPIs include Nexium, Prilosec and Prevacid, all available both as a prescription and over-the-counter (OTC). However, your doctor’s orders may actually do more harm than good in this instance, as these drugs tend to make your situation worse rather than better.

Smoking Gun Points to PPIs

Important information if you are taking medications. Nexium, Prevacid, Prilosec LawsuitYour cells use a proton pump to produce acid. PPI medications are designed to inhibit the proton pump and reduce the amount of acid produced. PPIs do not specifically target the cells in your stomach, and stomach acid is usually not the primary trigger behind chronic heartburn.

This class of drug is not specific, and instead will inhibit any cell with a proton pump producing acid, whether those cells are in your stomach or not. Researchers from Stanford University and Houston Methodist Hospital in Texas believe this is the smoking gun behind the variety of dangerous side effects linked to PPIs.1

The production of acid in your cells is associated with a specific cleanup process. The cells use acid to clean out end products and garbage from metabolism and cell function. When the acid is not present, there is a buildup of these toxins in the cells, which may lead to the development of a variety of significant health conditions.2

Excess stomach acid is not often the cause for your heartburn. Quite the opposite is true. Low amounts of stomach acid and the subsequent overgrowth of bacteria changes the digestion of carbohydrates, producing gas. The gas increases the pressure on the LES, releasing acid into the esophagus, creating heartburn.

While you may experience speedy relief of heartburn from immediate acting acid neutralizing medications such as TUMS, long-acting medications such as PPIs may increase your risk of heartburn over time.3

When Acid Levels Change, It Damages Your Body’s Ability to Function Properly

Proton pump inhibiting antacids such as omeprazole, lansoprazole, nexium and others can cause Alzheimer's... is the risk worth it?

 

When PPIs were first approved by the U.S. Food and Drug Administration (FDA), they were designed to be taken for no more than six weeks. However, today it is not uncommon to find people who have been taking these drugs for more than 10 years.4 Long-term use has been associated with a number of different problems, including:

Bacterial Overgrowth

Long-term use of PPIs encourages overgrowth of bacteria in your digestive tract.5 Bacterial overgrowth leads to malabsorption of nutrients and has been linked to inflammation of the stomach wall.6

Reduced Absorption of Nutrients

One of the most common causes of impaired function of digestion and the absorption of nutrients is the reduction of stomach acid production.

This occurs in both the elderly and individuals on long-term antacid treatments, such as PPIs.7Acid breaks down proteins, activates hormones and enzymes and protects your gut against overgrowth of bacteria.

Lack of acid results in iron and mineral deficiencies and incomplete digestion of proteins. This may also lead to a vitamin B12 deficiency.8 PPIs are also linked to a reduced absorption of magnesium. Low magnesium levels may lead to muscle spasms, heart palpitations and convulsions.9

Low Stomach Acid

PPIs reduce the amount of stomach acid. Symptoms include heartburn, indigestion, bloating, diarrhea, burping, burning and flatulence.10

Decreased Resistance to Infection

Your mouth, esophagus and intestines are home to a healthy growth of bacteria, but your stomach is relatively sterile. Stomach acid kills most of the bacteria coming from your food or liquids, protecting your stomach and your intestinal tract from abnormal bacterial growth.11

At the same time, the acid prevents the bacteria growing in your intestines from moving into your stomach or esophagus.

Reducing stomach acid changes the pH of your stomach and allows external bacteria to grow. PPIs may reduce acid between 90 and 95 percent, increasing your risk of salmonella, c. difficile, giardia and listeria infections.12,13

Other studies have linked the use of acid-reducing drugs to the development of pneumonia, tuberculosis (TB) and typhoid.14,15,16

The distortion of the gut microbiome affects your immune system and may increase your overall risk of infection. In vitro studies, those done on cells in test tubes, have found PPIs damage the function of white blood cells, responsible for fighting infection.17

Increased Risk of Bone Fractures

Lowering stomach acid production may also reduce the amount of calcium absorption, which in turn may lead to osteoporosis.

Researchers have linked long-term, dose-dependent use of PPIs with increased risk of hip fracture. The longer you take the medication and the more you take, the higher your risk of fracture.18

Antacids and Aspirin

In addition to the side effects listed above, researchers are discovering other health conditions associated with the use of PPIs and other acid reducing drugs.

Even while on PPI medication, you may experience occasional heartburn. Immediate acting antacids used to neutralize the acid in your esophagus may offer relief. Just be aware that this is really only adding insult to injury.

What’s worse, some antacids also contain aspirin, which may heighten your risk of adverse effects. In 2009, the FDA issued a warning about severe bleeding associated with the use of aspirin.

Since that time, the FDA has recorded eight cases of severe bleeding resulting from using over-the-counter antacids to neutralize heartburn.19 In some of those cases, the individual required a blood transfusion to stabilize their condition.

In a statement, Dr. Karen Murry Mahoney, deputy director of the division of nonprescription drug products, said:

“Take a close look at the Drug Facts label, and if the product has aspirin, consider choosing something else for your stomach symptoms.

Unless people read the Drug Facts label when they’re looking for stomach symptom relief, they might not even think about the possibility that a stomach medicine could contain aspirin.”20

What Barrett’s Esophagus Means to You

Long-term gastric reflux and heartburn may lead to Barrett’s Esophagus. This is a change in the cellular structure of the lining of your esophagus in response to chronic exposure to acid. Risk factors for Barrett’s Esophagus include:

Males Older age Tobacco use
Obesity Alcohol use Caucasian or African-American

The risk of developing cancer of the esophagus is significantly higher when you have Barrett’s Esophagus. In past years, the more common form of skin cancer has been squamous cell carcinoma. However, researchers have now discovered if you have taken PPIs for an extended period of time and have developed Barrett’s Esophagus, you have an increased risk of a more aggressive form called adenocarcinoma.

As recently as 1975, 75 percent of the esophageal cancers diagnosed were squamous cell carcinomas. More amenable to treatment and less aggressive then adenocarcinoma, the numbers have radically shifted in the past 30 years.21 The rate of squamous cell carcinoma has declined slightly, but the number of diagnosed adenocarcinoma of the esophagus has risen dramatically.

In 1975, 4 people per million were diagnosed with adenocarcinoma, and in 2001 it rose to 23 people per million, making it the fastest growing cancer in the U.S. according to the National Cancer Institute (NCI).22

Adenocarcinoma is now diagnosed in 80 percent of all esophageal cancers.23 Researchers theorized PPIs would protect people with Barrett’s Esophagus from adenocarcinoma, but found the reverse to be true. Not only did PPIs not protect the esophagus, but instead there was a dramatic increase in the risk of this deadly cancer, discovered in two separate studies.24,25

PPIs May Raise Your Risk for Dementia, Kidney Disease and Heart Attacks

PPIs affect all cells in your body, which may explain why they have been linked to such deadly conditions as kidney disease, heart attacks and dementia. In the past, PPIs were linked to acute interstitial nephritis, an inflammatory process in the kidneys. In a recent study of over 10,000 participants, researchers found another link to chronic kidney disease.26

The team found that those using PPIs to treat heartburn were more likely than other individuals on different heartburn medications to suffer chronic kidney disease or kidney failure over a five-year period.

Dr. Ziyad Al-Aly, one of the researchers and a kidney specialist with the Veterans Affairs St. Louis Health Care System, said the findings illuminated a significant point: “I think people see these medications at the drug store and assume they’re completely safe. But there’s growing evidence they’re not as safe as we’ve thought.

PPIs have also been linked to dementia in people over age 75. In a study evaluating over 73,000 people over age 75 without any signs of dementia at the outset of the study, researchers made a startling connection. Of the individuals who developed dementia in the following seven years, those who regularly used PPIs had a significantly higher risk of the condition.

A large data-mining study performed by researchers from Stanford University discovered PPIs were also associated with an increased risk of heart attack, while other long-term heartburn medications were not.

Health and Wellness Associates
EHS Telehealth

WordPress:  https://healthandwellnessassociates.co/

Rx to Wellness, Uncategorized

Do You need to be taking Magnesium?

     Do You need to be taking Magnesium

 

mag

  • Magnesium is required for the healthy function of most cells, especially your heart, kidneys and muscles
  • Low magnesium is a powerful predictor of heart disease, and recent research shows even subclinical magnesium deficiency can compromise your cardiovascular health
  • Low magnesium will impede your cellular metabolic function and deteriorate mitochondrial function, and is a component necessary for the activation of vitamin D
  • Top reasons to optimize your magnesium level include optimization and regulation of vitamin D, preventing migraines and depression, improving brain plasticity and protecting your heart health
  • Magnesium is also important for the prevention of kidney and liver damage, bacterial and fungal infections, impotence, multiple sclerosis, Alzheimer’s disease, premenstrual syndrome, osteoporosis, muscle cramps, Type 2 diabetes and mortality from all causes

 

You are definitely deficient in Magnesium if  :

 

You suffer from Migraines

You take Vitamin D

Do You have Crohns, Celiac or any digestive inflammation?

Are you depressed, on anti-depressants, or just SAD?

Have burst of anger, aggression, or you snap?

Memory?

Cardiac Issues, including High or Low Blood Pressure

Stroke

Diabetes

 

Ask your healthcare worker how much is the correct dosage for your body and your concerns.  If they dont give you an exact amount, they do not know what they are doing.

Contact us if you need assistance;

Health and Wellness Associates

healthwellnessassociates@gmail.com