Lifestyle, Uncategorized

New Male Contraceptive?

New Male Contraceptive?


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I’ve heard there’s a new male contraceptive in the works. Can you tell me when it is likely to become available?
A number of male contraceptive methods are under development, but the one that has gotten the most attention lately is a birth control pill that appears to be safe when taken daily. Called DMAU (short for dimethandrolone undecanoate), it is being developed by the U.S. National Institutes of Health at the University of Washington in Seattle and the Harbor-UCLA Medical Center in Torrance, CA.

The pill already has been tested in 83 men ages 18 to 50 in three doses: 100, 200 and 400 milligrams in two different formulations. The men who participated received either DMAU or a placebo, which they took once a day with food. The researchers reported that the 400 mg dose led to “marked suppression” of testosterone and reduced levels of two other hormones required for sperm production. Study leader Stephanie Page, M.D., Ph.D., a professor of medicine at the University of Washington, reported that very few of the men participating described symptoms consistent with testosterone deficiency or excess, and none of them developed serious side effects. Dr. Page noted that the men taking DMAU gained some weight and that their HDL (“good”) cholesterol declined, although she described both these changes as “mild.”

Dr. Page wrote that many men say they would prefer a daily pill as a reversible contraceptive, instead of long-acting injections or topical gels, which are also in development. She added that longer-term studies of DMAU are underway to confirm that taken daily, the drug blocks sperm production.

Development of a reliable birth control pill for men hasn’t been easy. Earlier studies found that some forms of oral testosterone delivered in a single pill can damage the liver or that the pills clear the body too quickly to be useful. DMAU contains a long-chain fatty acid that helps keep the contraceptive in the body longer.

In the works elsewhere is a gel called Nestorone-Testosterone that must be applied to the arms and shoulders daily. The hormone progestin in the gel shuts down hormones that stimulate testosterone production. An international study with 420 couples reportedly is testing whether the gel is safe and effective at preventing conception.

Another approach being investigated in India is temporary, nonsurgical vasectomy. It involves injecting a gel into sperm-carrying tubes in the scrotum. The gel damages sperm, leading to infertility. This treatment, called RISUG for “reversible inhibition of sperm under guidance,” can be undone with a second shot that breaks down the gel. I’ve read that some 540 men in India have received the treatment and that it has continued to prevent pregnancy in their partners for more than 13 years.

Despite these developments, it’s unlikely that a male contraceptive in pill or gel form will become available any time soon. For now, men should continue to use condoms, undergo vasectomy, or rely on women’s contraceptive use to prevent unwanted pregnancies.

Health and Wellness Associates

Lifestyle, Uncategorized

Ibuprofen Linked with Male Infertility



Ibuprofen Linked with Male Infertility


The widely-used over-the-counter painkiller ibuprofen may pose a threat to male fertility, suggests a small new study.


Researchers found that young men who took ibuprofen in doses commonly used by athletes developed a hormonal condition linked to reduced fertility, CNN reported.


The findings were published in the journal Proceedings of the National Academy of Sciences.


The study included 31 men, ages 18-35. Fourteen of them took a daily dosage of ibuprofen that many professional and amateur athletes take: 600 milligrams twice a day. This 1200-mg-per-day dose is the maximum limit listed on the labels of generic ibuprofen products, CNN reported.


The other 17 men in the study took a placebo.


Within 14 days, the men taking the ibuprofen developed the hormonal condition linked with lower fertility. If it does occur in men, this condition typically begins in middle age.


While “it is sure” that the hormonal effects in the study participants who used ibuprofen for only a short time are reversible, it’s unknown whether this is true after long-term ibuprofen use, study co-author Bernard Jegou, director of the Institute of Research in Environmental and Occupational Health in France, told CNN.


Even though this was a small study and further research is needed, the findings are important because ibuprofen is one of the most widely-used medications, Erma Drobnis, an associate professional practice professor of reproductive medicine and fertility at the University of Missouri, Columbia, told CNN.


She was not involved in the study.


Jegou agreed that more study is needed to answer a number of questions, including how low doses of ibuprofen affect male hormones and whether long-term effects are reversible, CNN reported.


Advil and Motrin are two brand names for ibuprofen.


The Consumer Healthcare Products Association is a trade group that represents manufacturers of over-the-counter medications and supplements. The association “supports and encourages continued research and promotes ongoing consumer education to help ensure safe use of OTC medicines,” spokesman Mike Tringale told CNN.

“The safety and efficacy of active ingredients in these products has been well documented and supported by decades of scientific study and real-world use,” he added.


Please call us with your concerns about your personal healtcare.

Health and Wellness Associates


Dr P Carrothers

312-972-9355 (WELL)

Health and Disease, Lifestyle

Different Treatments for Prostate Cancer Means Different Side Effects


Treatments for Prostate Cancer Have Different Side Effects


The long-term side effects of different prostate cancer treatments vary –

and knowing that may help men decide which one is right for them.


That’s the conclusion of two new studies published March 21 in the Journal of the American Medical Association.


Both followed men who had early stage prostate cancer treated with “modern” approaches — including the latest surgical and radiation techniques. And both found that side effects sometimes persisted for up to three years.


The specifics, however, varied.


Many men had surgery to remove the prostate. Overall, they tended to have greater declines in their sexual function, versus men who chose radiation or “active surveillance.”


They were also more prone to urinary incontinence.


On the other hand, men treated with radiation typically had more problems with bowel function. If they also received hormonal therapy, they were also at risk of hormone-related symptoms — such as hot flashes and breast enlargement.

On the brighter side, the issues with radiation were mainly limited to the first year after treatment, said Dr. Daniel Barocas, the lead researcher on one of the studies.


Not surprisingly, both studies found, men who opted for surgery or radiation had more long-term symptoms than those who chose active surveillance.


With that approach, men put off treatment in favor of having their cancer monitored with periodic blood tests and biopsies.


Active surveillance is an option for prostate cancer because the disease is often slow-growing and may never progress to the point where it threatens a man’s life.


But that doesn’t necessarily mean active surveillance is the best option for any one man, said Barocas. He’s an associate professor of urologic surgery at Vanderbilt University in Nashville.


Much depends on whether the cancer is “low-risk” or not, he explained. Low-risk prostate cancers have characteristics that mark them as less aggressive.


“If you’re in that low-risk group,” Barocas said, “active surveillance might be the best choice, to avoid treatment side effects.”


But for men with more aggressive prostate tumors, treatment is typically advised to boost their long-term survival.

For those patients, Barocas said, “it’s pretty clear that treatment is better than no treatment.”


Dr. Freddie Hamdy is a professor of surgery at the University of Oxford in England.


In general, he said, research suggests that when men with low-risk prostate cancer are carefully selected for active surveillance, they have “very low” death rates from the disease.


For some men, active surveillance might be anxiety-provoking, said Hamdy, who wrote an editorial published with the studies.


But, he added, his own research has found that men on active surveillance do not have higher rates of anxiety or depression than prostate cancer patients who choose immediate treatment.


“The anxiety generated in many of these patients is more likely to be related to the diagnosis of cancer, and the fact that [they] have to live with its consequences, irrespective of the treatment that they receive,” Hamdy said.


For their study, Barocas and his colleagues followed 2,550 men diagnosed with prostate cancer between 2011 and 2012. All had tumors that were confined to the prostate. Almost 60 percent had surgery; another 23.5 percent had external radiation; and 17 percent chose active surveillance.


Three years later, men who’d had surgery gave lower ratings to their sexual function, versus the two other groups. They also had more trouble with urinary incontinence: 14 percent said they had a “moderate or big problem” with urine leakage, compared with 5 to 6 percent of men in the other groups.


Radiation, meanwhile, carried the biggest risks of bowel problems and hormonal side effects. But that faded by year three.


The second study — of more than 1,100 men with early stage cancer — had similar findings.


Surgery carried higher risks of sexual dysfunction and urine leakage. For instance, of men with normal sexual function before surgery, 57 percent reported “poor” function two years later, the University of North Carolina researchers found.


External radiation, again, caused more short-term bowel problems. The study also included men who’d undergone brachytherapy — a type of internal radiation that implants radioactive “seeds” in the prostate. Those patients had more issues with urinary tract obstruction and irritation.


So what’s a man to do with that information? According to Barocas, patients can talk to their doctor about the types of side effects that might occur with each treatment — then decide what they can personally live with.


“If, for example, you already have poor sexual function — as many patients in our study did — that side effect might not mean as much to you,” Barocas said.


For a man with low-risk prostate cancer, he noted, the risk of any treatment side effect might not be “acceptable.”


Hamdy made another point: While robot-assisted surgery has become the go-to approach, it has the same types of side effects that traditional open surgery always had. They are also finding that there are parts of the robotic surgery equipment that can not be sterilized and thus various bacteria have been found in surgical rooms, that are not being addressed yet.


What should you do?


Stop your sedentary lifestyle!   Men who develop prostate cancer are usually less active than they have been in their past.  Change that. Get up walk.


Also, stop the depression.  Stop sitting around and feeling sorry for yourself.   This has been a common thread in men who develop prostate problems.


Eat right!   Stop eating out, stop snacking throughout the day on garbage foods!


If you need help in turning this problem around, call us!


Health and Wellness Associates


P Carrothers





Mens Health



If you are a man suffering

from poor sexual health, including impotence, low sperm count and infertility,

your body could be lacking the essential mineral zinc.

To be safe, get your zinc from foods which contain good amounts of the mineral. These include almonds,

Brazil nuts, buckwheat, ginger, green peas, hazel nuts, lima beans, oats,

parsley, peanuts, pecans, potatoes, pumpkin seeds, rye, sunflower seeds,

turnips, walnuts, whole wheat, fish such as herring and sardines, beef, lamb,

pork, liver, dairy products, egg yolks, poultry, shellfish, seafood, as well as

oysters, which are particularly high in zinc.


Health and Wellness Associates



Foods, Health and Disease, Uncategorized

Tomatoes and Men’s Strokes



Tomatoes and Strokes in Men

Sauced, stuffed, deep-fried, or au natural – tomatoes are a key part of many people’s diets. Now, new research suggests that eating this juicy fruit and its products could lower the risk of stroke in men, making it much more than a delicious ingredient. Other foods that are known to lower stroke risk, in MEN, are chocolate, whole grains, citrus fruits, low-fat dairy, beans, nuts, leafy greens, and fish.

Do you know someone who could benefit from this information, please share.


Health and Wellness Associates